Pharmacological action Cancer Treatment
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Sulforaphene

Pharmacological action Cancer Treatment
Product Name
Sulforaphene
CAS No.
592-95-0
Chemical Name
Sulforaphene
Synonyms
sativin;RAPHANIN;Sul aphene;sulforaphene;Sulphoraphen;L-SULFORAPHENE;S-SULFORAPHENE;L-SULPHORAPHENE;SULFORAPHENE, L-;Sulforaphen (6CI)
CBNumber
CB1686355
Molecular Formula
C6H9NOS2
Formula Weight
175.27
MOL File
592-95-0.mol
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Sulforaphene Property

alpha 
D19 -107° (c = 1.37 in chloroform); D14 -136° (c = 1.38 in alcohol)
Boiling point:
bp0.015 125-130°
Density 
1.16±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator, Under inert atmosphere
solubility 
Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly), Ethylacetate (Slightly)
form 
Slightly yellowish liquid.
color 
Colourless to Yellow
CAS DataBase Reference
592-95-0
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
17152
Product name
L-Sulforaphene
Purity
≥98%
Packaging
1mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
17152
Product name
L-Sulforaphene
Purity
≥98%
Packaging
5mg
Price
$166
Updated
2024/03/01
Cayman Chemical
Product number
17152
Product name
L-Sulforaphene
Purity
≥98%
Packaging
10mg
Price
$275
Updated
2024/03/01
TRC
Product number
S699440
Product name
Sulforaphene
Packaging
10mg
Price
$185
Updated
2021/12/16
ChemScene
Product number
CS-0022676
Product name
Sulforaphene
Purity
98.01%
Packaging
10mg
Price
$202
Updated
2021/12/16
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Sulforaphene Chemical Properties,Usage,Production

Pharmacological action

Sulforaphene, or raphanin, is the main sulfur component found in radish seeds of Raphanus sativus and is also found in broccoli and red cabbage. It was first described by G. Ivanovics and S. Horvath in 1947. Sulforaphene inhibits activity of viruses, some fungi and various bacteria including Staphylococcus, Streptococcus, Pneumococcus and Escherichia coli. The effect is stronger against Gram-positive than Gram-negative bacteria and against DNA than RNA viruses; it is suppressed by serum and by sulfur compounds such as hydrogen sulfide, mercaptoacetic acid, cystine and glutathione. The antibacterial, antifungal and antiviral effects from consuming radishes were recognized in traditional Chinese medicine. However, in the abstract to his 1947 paper, Ivanovics noted that because sulforaphene is highly toxic, it did not "hold the promise of a useful therapeutic agent".

Cancer Treatment

Sulforaphene may be a potential anti-triple negative breast cancer natural compound and its antiproliferation effects may be mediated by tumor suppressor Egr1; it has chemotherapeutic potential, it promotes Bax/Bcl2, MAPK-dependent human gastric cancer AGS cells apoptosis and inhibits migration via EGFR, p-ERK1/2 down-regulation; it enhances radiosensitivity of hepatocellular carcinoma through suppression of the NF-κB pathway. Sulforaphene has anti-proliferative and antibacterial properties. Sulforaphene also has herbicidal activity, the ED50 of it against velvetleaf seedlings was approximately 2×10-4 M.

Uses

Sulforaphene is an extract from the seeds of Raphanus sativus and displays anti-inflammatory and anti-cancer activity.

Synthesis Reference(s)

Tetrahedron, 22, p. 2139, 1966 DOI: 10.1016/S0040-4020(01)82133-5

Sulforaphene Preparation Products And Raw materials

Raw materials

Preparation Products

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Sulforaphene Suppliers

China 106 Germany 1 India 1 Switzerland 1 United Kingdom 4 United States 17 Global 130
Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
Advantage
58
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View Lastest Price from Sulforaphene manufacturers

BINBO BIOLOGICAL CO.,LTD
Product
Sulforaphene 592-95-0
Price
US $0.00/kg
Min. Order
1kg
Purity
>98%
Supply Ability
1000 kg
Release date
2024-04-25
Shanghai Standard Technology Co., Ltd.
Product
Sulforaphene 592-95-0
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-05-12
Career Henan Chemical Co
Product
Sulforaphene 592-95-0
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200KG
Release date
2020-01-12

592-95-0, SulforapheneRelated Search:

Fluorescein isothiocyanate Tiglic aldehyde 1,4-PHENYLENE DIISOTHIOCYANATE Phenyl isothiocyanate GLUCOTROPAEOLIN Z-LIGUSTILIDE ALPHA-CARYOPHYLLENE Hydroxycitric acid Xanthiside Muscone ISOQUERCITRIN ERUCIN Allyl isothiocyanate ISOTHIOCYANIC ACID 3-BUTEN-1-YL ESTER SULFORAPHENE, L-(RG) Sulforaphene ISOTHIOCYANATE, POLYMER-BOUND, 200-400

  • (E)-4-Isothiocyanato-1-(methylsulfinyl)-1-butene
  • sativin
  • sulforaphene
  • S-Sulforaphenefromradishseeds
  • SULFORAPHANE, DL-(SH)
  • 1-Butene,4-isothiocyanato-1-(Methylsulfinyl)-
  • L-SULFORAPHENE
  • L-SULPHORAPHENE
  • 4-isothiocyanato-1-(methylsulfinyl)-1-buten
  • 4-isothiocyanato-1-(methylsulfinyl)-1-butene
  • isothiocyanicacid,4-(methylsulfinyl)-3-butenylester
  • Sul aphene
  • 4-Methylsulfinylbut-3-enyl isothiocyanate
  • Isothiocyanicacid, 4-(methylsulfinyl)-3-butenyl ester (7CI,8CI)
  • Sulforaphen (6CI)
  • SULFORAPHENE, L-
  • S-SULFORAPHENE
  • RAPHANIN
  • (-)4 ISOTHIOCYANATO-4R-METHYLSULFINYL)-1-BUTENE
  • 4-ISOTHIOCYANATO-4R(METHYLSULFINYL)-1-BUTENE
  • (-)4-ISOTHIOCYANATO-4S-(METHYLSULFINYL)-1-BUTENE
  • (-)-4-ISOTHIOCYANATO-(1R)-(METHYLSULFINYL)-1-BUTENE
  • (-)-4-ISOTHIOCYANATO-(1S)-(METHYLSUFINYL)-1-BUTENE
  • Sulforaphene USP/EP/BP
  • Sulphoraphen
  • 592-95-0
  • C6H9NOS2
  • Miscellaneous Natural Products